Thirty hormones as clear diagrams, twenty guided courses, an assistant and a 90-day plan. Scroll — the cascade builds itself in front of you.
No commitment · cancel in two taps from the app
"Why do I sleep badly?", "What is DHT?". In plain English, the way you’d ask a person.
Step by step, from the trigger to the final effect. Each node says what it does and what it triggers.
A node caught your eye? Open it and it unfolds. A follow-up question? The assistant answers without re-explaining everything.
No three-mile page to wade through. You ask the question, the app draws the answer.
Here is what actually happens between the brain and the testes, floor by floor. The other 29 hormones in the app are described at the same level of detail.
Its GnRH neurons do not flow continuously: they fire in bursts, every 60 to 120 minutes. It is the RHYTHM that carries the information, not the amount. A continuous infusion of GnRH shuts the axis down instead of switching it on — which is exactly how it is blocked in medicine.
It travels only a few millimetres, through a network of vessels reserved for it between the hypothalamus and the pituitary. It never reaches the general circulation: a blood test from your arm shows nothing of it.
The size of a pea. Its gonadotroph cells carry the GnRH receptors and translate the brain’s signal into a hormone released into the blood. It is the tipping point between the nervous and the hormonal.
It travels through the blood to the testes. Its twin, FSH, leaves from the same place but handles sperm production. A single GnRH burst commands both, in proportions decided by the burst frequency.
The Leydig cells catch LH and turn cholesterol into testosterone, through a chain of five enzymes. Yes, cholesterol: it is the raw material for every steroid hormone in the body.
Muscle, bone density, mood, libido, red blood cells. And a feedback loop: it goes on to slow the hypothalamus and the pituitary that ordered it. That feedback is what makes the axis stable — and why bringing it in from outside shuts internal production down.
They never work alone. Each one listens to the others, and most of the questions you ask about your body play out between two of them.
Schematic silhouette. The relative positions of the glands are correct, the body proportions are not.
At the centre of the brain. It only makes melatonin in darkness: evening light, even through closed eyes, is enough to delay it starting up.
The conductor. It makes almost nothing itself: it gives short orders to the pituitary, and the pituitary speaks to the rest of the body.
The size of a pea, it commands the thyroid, the adrenals and the gonads. When it stops, the whole floor below stops with it.
In front of the windpipe. It sets the speed at which each cell spends its energy — temperature, heart rate, transit, hair.
Sitting like hats on the kidneys. Two systems in one: adrenaline within seconds, cortisol within tens of minutes.
Two hormones answering each other: one puts sugar away, the other brings it back out. It is the balance between them that holds your blood sugar, not either one alone.
The last floor of the axis. They manufacture, and they send information back up: it is that feedback loop that stops the system running away with itself.
Not abstract ideas: assemblies of atoms you can turn around and look at. Their shape explains their behaviour — why some enter cells and others stay outside.
Four fused carbon rings. It is this compact, fatty shape that lets it cross the cell membrane and act directly on DNA — where protein hormones have to stay at the door.
The same skeleton as testosterone, give or take a few atoms. Three more oxygens and a side chain: that is all that separates the stress hormone from the strength hormone. The enzymes that make one can often make the other.
The top ring has become aromatic — flat, rigid, six carbons in a perfect ring. The aromatase enzyme performs that transformation, starting from testosterone. The two hormones are one reaction apart.
Made from serotonin, itself derived from the tryptophan on your plate. The flat double ring on the left is the indole core — the same building block as in serotonin. Evening light blocks the enzyme that performs the final step.
Two OH groups side by side on an aromatic ring: that is the catechol motif, the signature of this family. Small and charged, it does not cross the blood-brain barrier — the dopamine acting in your head is made on site.
It is dopamine two transformations later: one OH added to the chain, one methyl placed on the nitrogen. Three very different hormones — dopamine, noradrenaline, adrenaline — on the same assembly line.
Hydrogens are not drawn — the convention of the "heavy atom" model. Drag to turn the molecule.
The bonds between atoms are exact and checked against the molecular formula. The 3D geometry, however, is computed from standard bond lengths and angles: the overall shape is right, the fine stereochemistry is not. This is not a crystallographic structure, and we would rather write that than let you assume otherwise.
On one side, what you find when you search for "hypothalamic-pituitary axis". On the other, the same thing in Spibio.
Understanding is the start. The app is also there to decide what to do with it.
Every hormone with its cascade, what stimulates it, what holds it back, and what it really produces.
It answers short when you dig into the same subject, and starts a full diagram again when you change subject.
Built from your profile and your schedule. Day by day, with tick-off tracking.
Chapter by chapter, with the curves drawn out and a quiz at the end. Included in Spibio+.
These are Spibio real screens, rebuilt in HTML so they stay sharp at any size. Same wording, same colours, same layout — nothing is prettied up.
You ask your question in plain English. It answers, and it draws the diagram when that helps. Three levels of detail, from simple to technical.
Six areas scored separately. The chart shows where you already hold up and where the same effort pays off most.
Written from your profile: your age, your activity, your schedule. It explains its reasoning instead of handing you a list.
Each protocol gets ticked off. The next phase does not start until the previous one holds.
None of them is bad. They just answer a different question.
| Searching the web | General-purpose AI | Videos | Spibio | |
|---|---|---|---|---|
| A visual, structured answer | No | No | Sometimes | Yes |
| Written for a teenager, no jargon | No | Varies | Varies | Yes |
| Adjustable level of detail | No | If you know how to ask | No | Yes |
| Says plainly what doesn’t work | Varies | Varies | Rarely | Yes |
| Leads to a concrete plan | No | No | No | Yes |
A whole section devoted to appearance, built like the rest of Spibio: each protocol starts from a real mechanism of the body, says what works, what doesn’t, and what is dangerous. No supplement recommended, no dosage, no promises.
Skin, sleep, body composition, face and posture, hair, lifestyle. You come out with your 3 priority levers. Included in your subscription, no Optimization add-on.
For each one: the biological mechanism at play, the concrete actions, what you really shouldn’t do, and the level of evidence stated honestly.
The plan is built from your assessment: the foundations first, then the levers that demand consistency, then the details.
A morning / daytime / evening routine, ticked off day after day. Each habit links back to the protocol explaining why it’s there.
Each one holds its own protocols, with the same layout: the mechanism first, the actions next, what to stop doing, and the stated level of evidence.
The lowest areas of your assessment decide what goes into the plan. The rest waits its turn.
Putting in place what has the most effect for the least cost: sleep, sun protection, skin barrier, posture. Nothing advanced until those four hold.
Adding the levers that demand consistency: strength training, food, morning light, and the category where your assessment is weakest.
Working on the high-visual-return details once the base is solid: body composition, eyes, haircut and presentation.
The assessment scores six areas separately, because an average would hide exactly what needs work. You come out with your lowest three, in order.
These are four of the twelve real questions, with the same scoring. Answer them and watch the matching areas light up on the body: green where your base holds, amber where there is slack, red where there is the most to gain.
Four questions is only a preview. The full assessment asks 12, scores 6 areas and gives you your 3 priorities. It is included in your subscription.
Take the full assessmentSchematic silhouette. The relative positions of the glands are correct, the body proportions are not.
These are two different things, and confusing them makes both harder to understand. One answers your questions about the body. The other walks with you, day after day, on your plan.
You write your question in plain English — “why do I sleep badly?”, “what is DHT?”. It answers, and when the answer is a mechanism, it builds it as a diagram rather than a wall of text. A follow-up? It carries on without re-explaining everything from scratch.
Spi is your tracking space, and it stays private. You write freely about where you are — training, skin, sleep, mood. It reads your earlier notes, so it spots what changes: a routine kept several times in a row, or training dropped last week and picked up again this one.
When Spi attaches a consistency strip, a tick box or a mini diagram to its answer, it supplies no number, no date, no percentage. It only names the type of visual — and the app builds it from your real data. That is what guarantees a number on screen is yours, never a plausible invention.
Every protocol in the app shows its level of evidence. Three dots, visible before you even read the content. That is what separates a health app from an advice video.
Several converging controlled trials, or a mechanism so well established it is no longer debated. Example: sun protection and skin ageing.
The mechanism is clear and the studies point the right way, but they are few, short, or done on populations far from you.
Plausible, consistent with what we know about the body, but not demonstrated in humans under normal conditions. We say so, and we do not sell it as settled.
The six diagrams at the top of this page stay playable here, no account needed. The app itself opens with a subscription.
No commitment. Cancel in two taps from the app, with no email to send.
The 30 official diagrams are written in advance and reviewed, not generated on the fly. The assistant, on the other hand, can be wrong like any AI — it is there to help you understand a mechanism, never to make a diagnosis. If you have any doubt about your health, a doctor comes first.
The app is written to be understood from around secondary school age, with three adjustable levels of detail. It never recommends a supplement or a medication with a dosage, and it contains a safety page that is always accessible.
No — the app opens with a subscription. What stays open, with no account and no card, is this site: the six diagrams at the top of this page unfold as they are, and the 30 hormone pages each explain their mechanism in full.
No. The two subscriptions are independent: you can take one, the other, or both. Spibio+ covers the hormones, the assistant and the courses; Optimization covers appearance, the protocols and the 90-day plan.
Yes, in two taps from the app, with no email to send and no reason to give. Access stays active until the end of the period you have already paid for.
To run your account and your plan, nothing else. It is neither sold nor resold. The details are on the Privacy page.
Spibio already works like an app from your browser, and you can add it to your home screen. The App Store version is in the works.
The six diagrams at the top are playable here. All thirty are in the app.